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It is estimated that more than 39 million people will die from antibiotic-resistant infections between now and 2050, the analysis shows.

Updated: Jun 19


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According to a study published in The Lancet, more than 39 million people worldwide may die from antibiotic-resistant infections over the next 25 years.


A new study of the Global Antimicrobial Resistance Studies (GRAM) project is the first global analysis of antimicrobial resistance (AR) trends over time.


The study shows that between 1990 and 2021, more than a million people died annually as a result of AMR. The study also calculates that in 2050, 1.91 million people may die directly from AMR, which is 70% more per year compared to 2022. During the same period, the number of deaths involving AMR bacteria will increase by almost 75% - from 4.71 million to 8.22 million per year.


Between 1990 and 2021, AMR mortality among children under the age of five decreased by 50%, and among people aged 70 and over increased by more than 80%. These trends are expected to continue in the coming decades, with under-five mortality from children under the age of five worldwide halving by 2050 and more than halving among people aged 70 and over.


The results of the study highlight the urgent need for measures including infection prevention, vaccination, minimization of inappropriate use of antibiotics and research into new antibiotics to reduce the number of deaths from PPP projected for 2050.


According to a study published in The Lancet, more than 39 million people worldwide may die from antibiotic-resistant infections over the next 25 years.


A new study of the Global Antimicrobial Resistance Studies (GRAM) project is the first global analysis of antimicrobial resistance (AR) trends over time.


The study shows that between 1990 and 2021, more than a million people died annually as a result of AMR. The study also calculates that in 2050, 1.91 million people may die directly from AMR, which is 70% more per year compared to 2022. During the same period, the number of deaths involving AMR bacteria will increase by almost 75% - from 4.71 million to 8.22 million per year.


Between 1990 and 2021, AMR mortality among children under the age of five decreased by 50%, and among people aged 70 and over increased by more than 80%. These trends are expected to continue in the coming decades, with under-five mortality from children under the age of five worldwide halving by 2050 and more than halving among people aged 70 and over.


The results of the study highlight the urgent need for measures including infection prevention, vaccination, minimization of inappropriate use of antibiotics and research into new antibiotics to reduce the number of deaths from PPP projected for 2050.


"Antimicrobial drugs are one of the cornerstones of modern health care, and growing resistance to them is a serious cause for concern. These results highlight that AMR has been a major global health threat for decades, and this threat is growing. Understanding how trends in AMR mortality have changed over time and how they are likely to change in the future is vital for making informed decisions that will help save lives," said study author Dr. Mohsen Nagawi, head of the AMR research team at the Institute of Health Indicators (IHME) of the University of Washington, USA.

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